Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states

Table 2 Fishers Exact test to determine probability of overlap between differentially expressed miRNAs and differentially methylated regions in colon cancer and the regions of overlap

A
		Regions with Δ miRNA transcript		Genomic regions
Regions with Δ methylation		10		2707
Regions with no Δ methylation		18		72293
p-value		2.75e-8
B
Chromosome	Location	Object	Distance (bp)	Δ Methylation
X	133131074	miR-363
X	133131505	miR-20b
X	133135052	C-DMR	3547	0.45
X	133507562	C-DMR	462	0.39
X	133508024	miR-503
X	133508504	C-DMR	480	0.42
1	98284214	miR-137
1	98291025	C-DMR	6811	0.37
15	87712252	miR-9*
15	87712252	miR-9
15	87745140	C-DMR	32888	0.39
15	87749926	C-DMR		0.37
16	65755256	C-DMR	38469	0.47
16	65793725	miR-328
2	176711496	C-DMR	11781	0.37
2	176723277	miR-10b
2	219556012	C-DMR	18599	0.53
2	219574611	miR-375
22	21495270	miR-650
22	21526783	C-DMR	31513	-0.56
6	72169975	miR-30a-5p
6	72169975	miR-30a-3p
6	72185916	C-DMR	15941	0.38
6	72187453	C-DMR
8	41637116	miR-486
8	41676418	C-DMR	39302	-0.5

ISSN: 1471-2407