From: XPD codon 312 and 751 polymorphisms, and AFB1 exposure, and hepatocellular carcinoma risk
 | Controls | HCCs |  |  |  | ||
---|---|---|---|---|---|---|---|
XPD genotype | n | % | n | % | OR (95% CI) | Adjusted OR (95% CI)a | P trend |
XPD codon Asp312Asn | |||||||
   DDb | 453 | 63.6 | 364 | 58.9 | Reference | Reference |  |
   DNb | 200 | 28.1 | 190 | 30.7 | 1.18(0.92-1.51) | 1.12(0.83-1.51) | 0.460 |
   NNb | 59 | 8.3 | 64 | 10.4 | 1.35(0.93-1.97) | 0.89(0.56-1.41) | 0.620 |
XPD codon Lys751Gln | |||||||
   LLc | 464 | 65.2 | 272 | 44.0 | Reference | Reference |  |
   LGc | 187 | 26.3 | 222 | 35.9 | 2.03(1.58-2.59) | 1.75(1.30-2.37) | < 0.001 |
   GGc | 61 | 8.6 | 124 | 20.1 | 3.47(2.47-4.88) | 2.47(1.62-3.76) | < 0.001 |