Univariate analysis | Multivariate analysisa | |||
---|---|---|---|---|
Factor | Hazard ratiob | P | Hazard ratiob | P |
Egr-1 | ||||
Low expression (score 1) versus Egr-1 negative (score 0) | 1.59 (1.01-2.50) | 0.044 | 1.41 (0.89-2.24) | 0.143 |
Moderate-high expression (score 2-3) versus Egr-1 negative (score 0) | 1.95 (1.11-3.44) | 0.021 | 1.38 (0.76-2.49) | 0.285 |
Age (5 year intervals) | 1.19 (1.08-1.31) | 0.001 | 1.11 (0.99-1.25) | 0.078 |
Tumor type (Papillary versus solid/mixed) | 2.33 (1.43-3.80) | 0.001 | 1.78 (1.03-3.08) | 0.038 |
Tumor stage (T1 versus Ta) | 3.01 (2.07-4.38) | <0.001 | 0.42 (0.16-1.10) | 0.078 |
Tumor grade (High grade versus PUNLMP+low grade) | 3.42 (2.34-4.98) | <0.001 | 6.12 (2.27-16.55) | 0.000 |
Sex | 0.99 (0.63-1.56) | 0.981 | ||
Size (> 3 cm versus < 3 cm) | 1.02 (0.65-1.60) | 0.941 | ||
Bacillus Calmette-Guerin (BCG) treatment | 0.55 (0.32-0.93) | 0.026 | ||
Concomitant CIS | 1.02 (0.65-1.60) | 0.941 |