Figure 2
From: Assessing pathogenicity of MLH1 variants by co-expression of human MLH1 and PMS2genes in yeast
The MMR efficiency in yeast strains harbouring endogenous and/or human MMR genes. Each datum is the mean, with a 95% confidence interval indicated, of three independent experiments. Mean mutation rates are: Wild-type 2.19 × 10-6 ; MV100 1.74 × 104; MV200 6.05 × 10-5; MV300 8.86 × 10-5; MV400 2.25 × 10-6. Genotypes of strains are boxed. All prepared strains originated from W303 background [17].