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Table 3 Genes differentially expressed between serous invasive and low malignant potential tumors

From: Expression profiling identifies genes involved in neoplastic transformation of serous ovarian cancer

Genbank Acc. No.

Gene

Description

Fold difference1

p-Value

NM_003514

IGKC

Immunoglobulin kappa constant

13.18

0.00484

NM_284764

FTLL1

Ferritin, light polypeptide-like 1

2.18

0.00888

NM_031157

HNRPA1

Heterogeneous nuclear ribonucleoprotein A1

0.69

0.00451

NM_017594

DIRAS2

DIRAS family, GTP-binding RAS-like 2

0.63

3.82E-05

AL122074

SLIT3

Slit homolog 3

0.58

0.00957

NM_003391

WNT2

Wingless-type MMTV integration site family member 2

0.52

0.000932

BC001356

IFI35

Interferon-induced protein 35

0.51

0.000297

NM_016140

CGI-38

Brain specific protein

0.51

0.000161

NM_078469

BCCIP

BRCA2 and CDKN1A interacting protein

0.5

0.00657

NM_005014

OMD

Osteomodulin

0.5

0.000953

AF070574

MGC26885

Spermatogenesis associated 2-like

0.49

0.00657

NM_013360

ZNF222

Zinc finger protein 222

0.47

0.00484

NM_024645

FLJ13842

Zinc finger, matrin type 4

0.46

0.00484

NM_004212

SLC28A2

Solute carrier family 28

0.45

0.00115

NM_017581

CHRNA9

Cholinergic receptor, nicotinic, alpha 9

0.42

0.00264

NM_006926

SFTPA2

Surfactant, pulmonary-associated protein A2

0.42

0.000253

AL365404

GPR108

G protein-coupled receptor 108

0.36

7.20E-07

NM_013941

OR10C1

Olfactory receptor, family 10, subfamily C, member 1

0.32

1.34E-05

NM_006934

SLC6A9

Solute carrier family 6, member 9

0.31

2.00E-07

NM_004720

EDG4

Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4

0.25

3.91E-08

  1. P-values were set to < 0.01 and the Benjamini and Hochberg FDR Multiple Testing Correction was applied. 1 Fold difference in normalized means of invasive tumors (numerator) compared with low malignant potential tumors (denominator).