Figure 8
From: NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells
Survival of NKL expressing T-ALL cells. JURKAT cells transduced with MSX2, TLX1 or vector control, respectively, were treated for 16 h with pharmacological inhibitors of NOTCH signaling, NFkB activity, PI3K-signaling or PKC. Subsequent analysis of cell viability by MTT assay indicates differences in sensitivities. Values of JURKAT-vector cells were used as control. Bars show standard deviations.