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Figure 4 | BMC Cancer

Figure 4

From: Establishment of canine hemangiosarcoma xenograft models expressing endothelial growth factors, their receptors, and angiogenesis-associated homeobox genes

Figure 4

Angiogenic growth factors and their receptors immunolabeled in original HSAs and xenograft HSA tumors. Representative immunohistochemical results of VEGF-A, flt-1, flk-1, and bFGF in original HSAs and xenograft HSA tumors. All original HSAs had cytoplasmic immunoreactivity for VEGF-A (A: the original tumor of Re), flt-1 (C: the original tumor of Ju), flk-1 (E: the original tumor of Ud), and bFGF (G: the original tumor of Si). Immunoreactivity for VEGF-A (B: Re), flt-1 (D: Ju), flk-1 (F: Ud), and bFGF (H: Si) in all xenograft HSA tumors was detected in the same location as in the original tumors. Immunohistochemistry (IHC); bars: 50 μm.

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