Figure 6From: Topoisomerase I but not thymidylate synthase is associated with improved outcome in patients with resected colorectal cancer treated with irinotecan containing adjuvant chemotherapy OS (a) and DFS (b) in Topo I positive (red line) and Topo I negative (blue line) CPT-11 treated patients (log-rank p = 0.028 and p = 0.323, respectively). OS (c) and DFS (d) in Topo I positive (red line) and Topo I negative (blue line) non-CPT-11 treated patients (log-rank p = 0.478 and p = 0.945, respectively).Back to article page