Figure 5From: Topoisomerase I but not thymidylate synthase is associated with improved outcome in patients with resected colorectal cancer treated with irinotecan containing adjuvant chemotherapy OS (a) and DFS (b) in TS positive (red line) and TS negative (blue line) CPT-11 treated patients (log-rank p = 0.868 and p = 0.937, respectively). OS (c) and DFS (d) in TS positive (red line) and TS negative (blue line) non-CPT-11 treated patients (log-rank p = 0.062 and p = 0.035, respectively).Back to article page