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Figure 2 | BMC Cancer

Figure 2

From: Topoisomerase I but not thymidylate synthase is associated with improved outcome in patients with resected colorectal cancer treated with irinotecan containing adjuvant chemotherapy

Figure 2

Immunohistochemical detection of Topo I in TMA cores of colorectal carcinoma cases. Strong nuclear staining, graded as positive with a total score of 6/6 (a); moderate, diffused, predominantly cytoplasmic staining, graded as positive with a total score of 5/6 (b); mild focal nuclear and cytoplasmic staining, graded as low expression/negative with a total score of 2/6 (c). (Magnification: ×100).

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