Figure 1From: Topoisomerase I but not thymidylate synthase is associated with improved outcome in patients with resected colorectal cancer treated with irinotecan containing adjuvant chemotherapy Immunohistochemical detection of TS in TMA cores of colorectal carcinoma cases. Strong cytoplasmic staining, graded as positive with a total score of 6/6 (a); mild focal cytoplasmic staining, graded as negative with a total score of 2/6 (b); absence of staining in a signet-ring cell carcinoma, with a total score of 0/6 (c). (Magnification: ×100).Back to article page