MMP secretion of hepatoma cells with or without integrin α6β1 mAbs and siHAb18G/CD147 treatment. MMP levels of FHCC98 (A, B) and 7721 (A, C) cells. Bars represent the mean of triplicate samples; error bars represent standard deviation. Data are representative of three independent experiments. ***P < 0.01, * P < 0.05 versus corresponding cells with no antibody treatment.