Table 2 Univariate and Multivariable survival analyses of the subgroup of untreated patients, N = 102*

TIMP-1

Continuous variable

0.96 (0.63-1.45)

0.84

0.72 (0.39-1.33)

0.29

High vs. low

0.93 (0.58-1.49)

0.76

0.72 (0.39-1.33)

0.3

Multivariable

DFS

OS

HR (95% CI)

P

HR (95% CI)

P

TIMP-1

Continuous variable

0.95 (0.60-1.51)

0.84

0.80 (0.41-1.57)

0.52

High vs. low

0.95 (0.56-1.62)

0.86

0.80 (0.41-1.54)

0.5

Age

41-55 years vs. ≤ 40 years

0.53 (0.31-0.89)

0.02

0.40 (0.21-0.77)

0.01

Tumor size

Stage 2 (> 2 cm) vs. stage 1 (≤ 2 cm)

1.76 (0.93-3.33)

0.19

1.77 (0.72-4.36)

0.37

Stage 3 (>5 cm or chest wall/skin involvement) vs. stage 1 (≤ 2 cm)

1.35 (0.58-3.14)

2.01 (0.62-6.45)

Grade

Unknown vs. poor

0.70 (0.40-1.22)

0.39

0.83 (0.41-1.67)

0.51

Well/moderate vs. poor

0.74 (0.33-1.64)

0.54 (0.18-1.64)