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Table 2 Annotated genes with decreased expression in BON1 cells transfected with siRNA to ASCL1

From: Identification of Achaete-scute complex-like 1 (ASCL1) target genes and evaluation of DKK1 and TPH1 expression in pancreatic endocrine tumours

Gene Symbol

Gene Name

Location

Ratio

adj P Value

FAM87A

family with sequence similarity 87, member A

8p23.3

0,221

0,0000104

DKFZP761C1711

Hypothetical protein DKFZp761C1711

 

0,246

0,0000258

GABRA1

gamma-aminobutyric acid (GABA) A receptor, alpha 1

5q34-q35

0,260

0,0000172

GUSBP1

glucuronidase, beta pseudogene 1

7q21.11

0,277

0,0000104

TncRNA

trophoblast-derived noncoding RNA

11q13.1

0,284

0,0000104

LOC728411

Similar to Beta-glucuronidase precursor

5.

0,296

0,0000104

TTLL5

tubulin tyrosine ligase-like family, member 5

17q21.32

0,328

0,0001110

EBF1

Early B-cell factor 1

5q34

0,333

0,0000112

VPS13C

Vacuolar protein sorting 13 homolog C (S. cerevisiae)

15q21.3

0,341

0,0000150

RNF12

Ring finger protein 12

Xq13-q21

0,342

0,0000283

ASCL1*

achaete-scute complex homolog 1 (Drosophila)

12q22-q23

0,351

0,0000162

SORBS2

sorbin and SH3 domain containing 2

4q35.1

0,353

0,0000161

ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4

2q33.3-q34

0,359

0,0001092

FLJ38379

hypothetical protein FLJ38379

2q37.3

0,360

0,0001245

TCF12

Transcription factor 12

15q21

0,365

0,0000283

PGM5

phosphoglucomutase 5

9q13

0,365

0,0000499

RIT1

Ras-like without CAAX 1

1q22

0,366

0,0000150

ZCCHC7

Zinc finger, CCHC domain containing 7

9p13.2

0,371

0,0001730

LOC730168

hypothetical protein LOC730168///LOC732289

3q26.32

0,374

0,0000625

CFLAR

CASP8 and FADD-like apoptosis regulator

2q33-q34

0,374

0,0001083

C11orf80

chromosome 11 open reading frame 80

11q

0,375

0,0000579

CCAR1

Cell division cycle and apoptosis regulator 1

10q21.3

0,375

0,0000796

FAM81B

family with sequence similarity 81, member B

5q15

0,382

0,0000599

FLJ25770

hypothetical protein FLJ25770

4q21.1

0,383

0,0000181

LOC730390

SMA4///similar to SMA4

5q13

0,385

0,0000159

ZFAND6

Zinc finger, AN1-type domain 6

15q25.1

0,387

0,0000246

LOC728555

hypothetical protein LOC728555///LOC730391

5q13.2

0,388

0,0000151

GRAMD3

GRAM domain containing 3

5q23.2

0,394

0,0000136

CBFA2T2

core-binding factor, runt domain, alpha subunit 2

20q11

0,394

0,0000181

ZNF638

Zinc finger protein 638

2p13.2-p13.1

0,396

0,0019556

LOC728678

hypothetical protein LOC728678///LOC731914

3p22.3

0,397

0,0000150

CLCN5

chloride channel 5

Xp11.23-p11.22

0,398

0,0000170

ANXA13

annexin A13

8q24.13

0,412

0,0000181

RP11-506K6.3

Hypothetical LOC389362

6p25.2

0,415

0,0002632

FLJ23556

hypothetical protein FLJ23556

10q25.2

0,417

0,0000788

PFAAP5

Phosphonoformate immuno-associated protein 5

13q13.1

0,417

0,0000150

PCDHGA4

protocadherin gamma subfamily A, 4

5q31

0,419

0,0000274

LOC145474

hypothetical protein LOC145474

14q24.1

0,421

0,0003892

IFIT1

interferon-induced protein

10q25-q26

0,421

0,0006010

DKFZp547E087

hypothetical gene LOC283846

18p11.21

0,424

0,0000586

TXNIP

thioredoxin interacting protein

1q21.1

0,427

0,0000305

CDC14B

CDC14 cell division cycle 14 homolog B

9q22.33

0,432

0,0000885

RUFY2

RUN and FYVE domain containing 2

10q21.3

0,432

0,0001373

KLHL28

Kelch-like 28 (Drosophila)

14q21.3

0,435

0,0002095

MBNL2

Muscleblind-like 2 (Drosophila)

13q32.1

0,436

0,0000246

LOC730496

hypothetical protein LOC730496

1.

0,436

0,0000150

PRKAA1

protein kinase, AMP-activated, alpha 1 catalytic subunit

5p12

0,436

0,0002228

NR5A2

nuclear receptor subfamily 5, group A, member 2

1q32.1

0,438

0,0003777

LOC388743

similar to calpain 8

1q41

0,440

0,0000284

PTPN13

Protein tyrosine phosphatase, non-receptor type 13

4q21.3

0,441

0,0011559

RASAL2

RAS protein activator like 2

1q24

0,442

0,0003715

LOC730258

neuroblastoma breakpoint family, member 1, 3, 8, 10

1q21.1

0,443

0,0000150

ZNF518

Zinc finger protein 518

10q23.33

0,445

0,0002293

SCNN1A

sodium channel, nonvoltage-gated 1 alpha

12p13

0,445

0,0000176

CTAGE5

CTAGE family, member 5

14q13.3

0,446

0,0000617

LOC440895

similar to LIM and senescent cell antigen-like domains 3

2q13

0,446

0,0003164

PELI1

Pellino homolog 1 (Drosophila)

2p13.3

0,449

0,0001121

FAM98A

Family with sequence similarity 98, member A

2p22.3

0,449

0,0000499

BRWD2

bromodomain and WD repeat domain containing 2

10q26

0,450

0,0000602

C20orf74

chromosome 20 open reading frame 74

20p11.22

0,450

0,0000926

MALAT1

metastasis associated lung adenocarcinoma transcript 1

2p16.3

0,452

0,0001060

RTN4

reticulon 4

2p16.3

0,453

0,0004446

LOC654342

Similar to lymphocyte-specific protein 1

2p11.1

0,454

0,0000284

CYorf15B

chromosome Y open reading frame 15B

Yq11.222

0,455

0,0001245

SMOC2

SPARC related modular calcium binding 2

6q27

0,456

0,0002821

CAPN2

calpain 2, (m/II) large subunit

1q41-q42

0,457

0,0000460

HEL308

DNA helicase HEL308

4q21.23

0,459

0,0006091

PDCD6

Programmed cell death 6

5pter-p15.2

0,459

0,0000722

LOC285147

hypothetical protein LOC285147

2p25.2

0,460

0,0001063

TFF3

trefoil factor 3 (intestinal)

21q22.3

0,460

0,0010306

RIMBP2

RIMS binding protein 2

12q24.33

0,461

0,0000520

C10orf93

chromosome 10 open reading frame 93

10q26.3

0,462

0,0000950

SUCNR1

succinate receptor 1

3q24-q25.1

0,462

0,0000603

LOC151878

hypothetical protein LOC151878

3p14.3

0,463

0,0003715

LRRFIP1

Leucine rich repeat (in FLII) interacting protein 1

2q37.3

0,465

0,0000339

ADAM12

ADAM metallopeptidase domain 12 (meltrin alpha)

10q26.3

0,465

0,0003076

GART

Phosphoribosylglycinamide, phosphoribosylaminoimidazole

21q22.11

0,466

0,0003142

PLGLB1/2

plasminogen-like B2///plasminogen-like B1

2p11-q11

0,467

0,0007445

RET

ret proto-oncogene

10q11.2

0,467

0,0000247

POLQ

polymerase (DNA directed), theta

3q13.33

0,467

0,0002632

KIAA1632

KIAA1632

18q12.3-q21.1

0,468

0,0004005

ADAM28

ADAM metallopeptidase domain 28

8p21.2

0,469

0,0000950

MSI2

Musashi homolog 2 (Drosophila)

17q22

0,469

0,0000344

JMJD1C

jumonji domain containing 1C

10q21.2-q21.3

0,470

0,0001013

DST

dystonin

6p12.1

0,473

0,0001509

NT5E

5'-nucleotidase, ecto (CD73)

6q14-q21

0,474

0,0000288

LYST

lysosomal trafficking regulator

1q42.1-q42.2

0,475

0,0001027

SYK

Spleen tyrosine kinase

9q22

0,476

0,0003933

DLG1

Discs, large homolog 1 (Drosophila)

3q29

0,476

0,0006683

RASSF6

Ras association (RalGDS/AF-6) domain family 6

4q13.3

0,476

0,0006133

TRA2A

transformer-2 alpha

1p36.11

0,478

0,0000701

UBE2D3

ubiquitin-conjugating enzyme E2D 3

4q24

0,479

0,0002430

TMEM46

transmembrane protein 46

13q12.13

0,480

0,0000248

INADL

InaD-like (Drosophila)

1p31.3

0,480

0,0002693

TTC30A

tetratricopeptide repeat domain 30A

2q31.2

0,484

0,0003577

SNAP25

Synaptosomal-associated protein, 25 kDa

20p12-p11.2

0,484

0,0000189

PRO2852

hypothetical protein PRO2852

9.

0,485

0,0000460

MLLT3

myeloid/lymphoid or mixed-lineage leukemia

9p22

0,486

0,0004334

RBM6

RNA binding motif protein 6

3p21.3

0,488

0,0002432

PPP2R5C

protein phosphatase 2, regulatory subunit B',

14q32

0,488

0,0000241

GOPC

Golgi associated PDZ and coiled-coil motif containing

6q21

0,489

0,0006453

LAMA4

laminin, alpha 4

6q21

0,489

0,0001402

SFRS15

splicing factor, arginine/serine-rich 15

21q22.1

0,490

0,0000344

KIF13A

kinesin family member 13A

6p23

0,491

0,0001644

CLASP2

cytoplasmic linker associated protein 2

3p22.3

0,493

0,0004942

MMAA

Methylmalonic aciduria (cobalamin deficiency) cblA type

4q31.22

0,493

0,0002644

C1orf192

chromosome 1 open reading frame 192

1q23.3

0,494

0,0006859

hCG_2003663

hCG2003663

9q22.32

0,494

0,0006724

SMOC1

SPARC related modular calcium binding 1

14q24.2

0,494

0,0001073

REV3L

REV3-like, catalytic subunit of DNA polymerase zeta

6q21

0,496

0,0001092

SMAD1

SMAD family member 1

4q31

0,496

0,0004345

TWF1

twinfilin, actin-binding protein, homolog 1 (Drosophila)

12q12

0,497

0,0001687

FBXO9

F-box protein 9

6p12.3-p11.2

0,497

0,0000391

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BMC Cancer

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