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Table 2 Annotated genes with decreased expression in BON1 cells transfected with siRNA to ASCL1

From: Identification of Achaete-scute complex-like 1 (ASCL1) target genes and evaluation of DKK1 and TPH1 expression in pancreatic endocrine tumours

Gene Symbol Gene Name Location Ratio adj P Value
FAM87A family with sequence similarity 87, member A 8p23.3 0,221 0,0000104
DKFZP761C1711 Hypothetical protein DKFZp761C1711   0,246 0,0000258
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 5q34-q35 0,260 0,0000172
GUSBP1 glucuronidase, beta pseudogene 1 7q21.11 0,277 0,0000104
TncRNA trophoblast-derived noncoding RNA 11q13.1 0,284 0,0000104
LOC728411 Similar to Beta-glucuronidase precursor 5. 0,296 0,0000104
TTLL5 tubulin tyrosine ligase-like family, member 5 17q21.32 0,328 0,0001110
EBF1 Early B-cell factor 1 5q34 0,333 0,0000112
VPS13C Vacuolar protein sorting 13 homolog C (S. cerevisiae) 15q21.3 0,341 0,0000150
RNF12 Ring finger protein 12 Xq13-q21 0,342 0,0000283
ASCL1* achaete-scute complex homolog 1 (Drosophila) 12q22-q23 0,351 0,0000162
SORBS2 sorbin and SH3 domain containing 2 4q35.1 0,353 0,0000161
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 2q33.3-q34 0,359 0,0001092
FLJ38379 hypothetical protein FLJ38379 2q37.3 0,360 0,0001245
TCF12 Transcription factor 12 15q21 0,365 0,0000283
PGM5 phosphoglucomutase 5 9q13 0,365 0,0000499
RIT1 Ras-like without CAAX 1 1q22 0,366 0,0000150
ZCCHC7 Zinc finger, CCHC domain containing 7 9p13.2 0,371 0,0001730
LOC730168 hypothetical protein LOC730168///LOC732289 3q26.32 0,374 0,0000625
CFLAR CASP8 and FADD-like apoptosis regulator 2q33-q34 0,374 0,0001083
C11orf80 chromosome 11 open reading frame 80 11q 0,375 0,0000579
CCAR1 Cell division cycle and apoptosis regulator 1 10q21.3 0,375 0,0000796
FAM81B family with sequence similarity 81, member B 5q15 0,382 0,0000599
FLJ25770 hypothetical protein FLJ25770 4q21.1 0,383 0,0000181
LOC730390 SMA4///similar to SMA4 5q13 0,385 0,0000159
ZFAND6 Zinc finger, AN1-type domain 6 15q25.1 0,387 0,0000246
LOC728555 hypothetical protein LOC728555///LOC730391 5q13.2 0,388 0,0000151
GRAMD3 GRAM domain containing 3 5q23.2 0,394 0,0000136
CBFA2T2 core-binding factor, runt domain, alpha subunit 2 20q11 0,394 0,0000181
ZNF638 Zinc finger protein 638 2p13.2-p13.1 0,396 0,0019556
LOC728678 hypothetical protein LOC728678///LOC731914 3p22.3 0,397 0,0000150
CLCN5 chloride channel 5 Xp11.23-p11.22 0,398 0,0000170
ANXA13 annexin A13 8q24.13 0,412 0,0000181
RP11-506K6.3 Hypothetical LOC389362 6p25.2 0,415 0,0002632
FLJ23556 hypothetical protein FLJ23556 10q25.2 0,417 0,0000788
PFAAP5 Phosphonoformate immuno-associated protein 5 13q13.1 0,417 0,0000150
PCDHGA4 protocadherin gamma subfamily A, 4 5q31 0,419 0,0000274
LOC145474 hypothetical protein LOC145474 14q24.1 0,421 0,0003892
IFIT1 interferon-induced protein 10q25-q26 0,421 0,0006010
DKFZp547E087 hypothetical gene LOC283846 18p11.21 0,424 0,0000586
TXNIP thioredoxin interacting protein 1q21.1 0,427 0,0000305
CDC14B CDC14 cell division cycle 14 homolog B 9q22.33 0,432 0,0000885
RUFY2 RUN and FYVE domain containing 2 10q21.3 0,432 0,0001373
KLHL28 Kelch-like 28 (Drosophila) 14q21.3 0,435 0,0002095
MBNL2 Muscleblind-like 2 (Drosophila) 13q32.1 0,436 0,0000246
LOC730496 hypothetical protein LOC730496 1. 0,436 0,0000150
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 5p12 0,436 0,0002228
NR5A2 nuclear receptor subfamily 5, group A, member 2 1q32.1 0,438 0,0003777
LOC388743 similar to calpain 8 1q41 0,440 0,0000284
PTPN13 Protein tyrosine phosphatase, non-receptor type 13 4q21.3 0,441 0,0011559
RASAL2 RAS protein activator like 2 1q24 0,442 0,0003715
LOC730258 neuroblastoma breakpoint family, member 1, 3, 8, 10 1q21.1 0,443 0,0000150
ZNF518 Zinc finger protein 518 10q23.33 0,445 0,0002293
SCNN1A sodium channel, nonvoltage-gated 1 alpha 12p13 0,445 0,0000176
CTAGE5 CTAGE family, member 5 14q13.3 0,446 0,0000617
LOC440895 similar to LIM and senescent cell antigen-like domains 3 2q13 0,446 0,0003164
PELI1 Pellino homolog 1 (Drosophila) 2p13.3 0,449 0,0001121
FAM98A Family with sequence similarity 98, member A 2p22.3 0,449 0,0000499
BRWD2 bromodomain and WD repeat domain containing 2 10q26 0,450 0,0000602
C20orf74 chromosome 20 open reading frame 74 20p11.22 0,450 0,0000926
MALAT1 metastasis associated lung adenocarcinoma transcript 1 2p16.3 0,452 0,0001060
RTN4 reticulon 4 2p16.3 0,453 0,0004446
LOC654342 Similar to lymphocyte-specific protein 1 2p11.1 0,454 0,0000284
CYorf15B chromosome Y open reading frame 15B Yq11.222 0,455 0,0001245
SMOC2 SPARC related modular calcium binding 2 6q27 0,456 0,0002821
CAPN2 calpain 2, (m/II) large subunit 1q41-q42 0,457 0,0000460
HEL308 DNA helicase HEL308 4q21.23 0,459 0,0006091
PDCD6 Programmed cell death 6 5pter-p15.2 0,459 0,0000722
LOC285147 hypothetical protein LOC285147 2p25.2 0,460 0,0001063
TFF3 trefoil factor 3 (intestinal) 21q22.3 0,460 0,0010306
RIMBP2 RIMS binding protein 2 12q24.33 0,461 0,0000520
C10orf93 chromosome 10 open reading frame 93 10q26.3 0,462 0,0000950
SUCNR1 succinate receptor 1 3q24-q25.1 0,462 0,0000603
LOC151878 hypothetical protein LOC151878 3p14.3 0,463 0,0003715
LRRFIP1 Leucine rich repeat (in FLII) interacting protein 1 2q37.3 0,465 0,0000339
ADAM12 ADAM metallopeptidase domain 12 (meltrin alpha) 10q26.3 0,465 0,0003076
GART Phosphoribosylglycinamide, phosphoribosylaminoimidazole 21q22.11 0,466 0,0003142
PLGLB1/2 plasminogen-like B2///plasminogen-like B1 2p11-q11 0,467 0,0007445
RET ret proto-oncogene 10q11.2 0,467 0,0000247
POLQ polymerase (DNA directed), theta 3q13.33 0,467 0,0002632
KIAA1632 KIAA1632 18q12.3-q21.1 0,468 0,0004005
ADAM28 ADAM metallopeptidase domain 28 8p21.2 0,469 0,0000950
MSI2 Musashi homolog 2 (Drosophila) 17q22 0,469 0,0000344
JMJD1C jumonji domain containing 1C 10q21.2-q21.3 0,470 0,0001013
DST dystonin 6p12.1 0,473 0,0001509
NT5E 5'-nucleotidase, ecto (CD73) 6q14-q21 0,474 0,0000288
LYST lysosomal trafficking regulator 1q42.1-q42.2 0,475 0,0001027
SYK Spleen tyrosine kinase 9q22 0,476 0,0003933
DLG1 Discs, large homolog 1 (Drosophila) 3q29 0,476 0,0006683
RASSF6 Ras association (RalGDS/AF-6) domain family 6 4q13.3 0,476 0,0006133
TRA2A transformer-2 alpha 1p36.11 0,478 0,0000701
UBE2D3 ubiquitin-conjugating enzyme E2D 3 4q24 0,479 0,0002430
TMEM46 transmembrane protein 46 13q12.13 0,480 0,0000248
INADL InaD-like (Drosophila) 1p31.3 0,480 0,0002693
TTC30A tetratricopeptide repeat domain 30A 2q31.2 0,484 0,0003577
SNAP25 Synaptosomal-associated protein, 25 kDa 20p12-p11.2 0,484 0,0000189
PRO2852 hypothetical protein PRO2852 9. 0,485 0,0000460
MLLT3 myeloid/lymphoid or mixed-lineage leukemia 9p22 0,486 0,0004334
RBM6 RNA binding motif protein 6 3p21.3 0,488 0,0002432
PPP2R5C protein phosphatase 2, regulatory subunit B', 14q32 0,488 0,0000241
GOPC Golgi associated PDZ and coiled-coil motif containing 6q21 0,489 0,0006453
LAMA4 laminin, alpha 4 6q21 0,489 0,0001402
SFRS15 splicing factor, arginine/serine-rich 15 21q22.1 0,490 0,0000344
KIF13A kinesin family member 13A 6p23 0,491 0,0001644
CLASP2 cytoplasmic linker associated protein 2 3p22.3 0,493 0,0004942
MMAA Methylmalonic aciduria (cobalamin deficiency) cblA type 4q31.22 0,493 0,0002644
C1orf192 chromosome 1 open reading frame 192 1q23.3 0,494 0,0006859
hCG_2003663 hCG2003663 9q22.32 0,494 0,0006724
SMOC1 SPARC related modular calcium binding 1 14q24.2 0,494 0,0001073
REV3L REV3-like, catalytic subunit of DNA polymerase zeta 6q21 0,496 0,0001092
SMAD1 SMAD family member 1 4q31 0,496 0,0004345
TWF1 twinfilin, actin-binding protein, homolog 1 (Drosophila) 12q12 0,497 0,0001687
FBXO9 F-box protein 9 6p12.3-p11.2 0,497 0,0000391
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BMC Cancer

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