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Table 1 Annotated genes with increased expression in BON1 cells transfected with siRNA to ASCL1

From: Identification of Achaete-scute complex-like 1 (ASCL1) target genes and evaluation of DKK1 and TPH1 expression in pancreatic endocrine tumours

Gene Symbol

Gene Name

Location

Ratio

adj p Value

RBM24

RNA binding motif protein 24

6p22.3

4,708

0,0000391

HAS2

hyaluronan synthase 2

8q24.12

3,279

0,0002805

MYCN

v-myc myelocytomatosis viral related oncogene,

2p24.1

2,777

0,0000305

C13orf15

chromosome 13 open reading frame 15

13q14.11

2,594

0,0000701

APCDD1

adenomatosis polyposis coli down-regulated 1

18p11.22

2,569

0,0000305

LGR5

leucine-rich repeat-containing G protein-coupled receptor 5

12q22-q23

2,540

0,0003188

DKK1*

dickkopf homolog 1 (Xenopus laevis)

10q11.2

2,349

0,0000155

TPH1*

Tryptophan hydroxylase 1

11p15.3-p14

2,325

0,0002805

ID4

Inhibitor of DNA binding 4

6p22-p21

2,317

0,0001962

PVRL3

poliovirus receptor-related 3

3q13

2,295

0,0000949

TIMP2

TIMP metallopeptidase inhibitor 2

17q25

2,286

0,0000200

ASAM

adipocyte-specific adhesion molecule

11q24.1

2,254

0,0002763

SPOCK1

sparc/osteonectin, cwcv and kazal-like domains

5q31

2,251

0,0000796

NRXN3

neurexin 3

14q31

2,246

0,0002025

KL

klotho

13q12

2,240

0,0000150

GPD2

glycerol-3-phosphate dehydrogenase 2 (mitochondrial)

2q24.1

2,238

0,0000155

CLIC5

chloride intracellular channel 5

6p21.1-p12.1

2,235

0,0000313

EMG1

EMG1 nucleolar protein homolog (S. cerevisiae)

12p13

2,230

0,0000489

DRD1IP

dopamine receptor D1 interacting protein

10q26.3

2,219

0,0001121

CXCR7

chemokine (C-X-C motif) receptor 7

2q37.3

2,216

0,0000862

STOML3

stomatin (EPB72)-like 3

13q13.3

2,196

0,0003867

SI

sucrase-isomaltase (alpha-glucosidase)

3q25.2-q26.2

2,181

0,0000701

FGF13

fibroblast growth factor 13

Xq26.3

2,178

0,0000288

CHM

choroideremia (Rab escort protein 1)

Xq21.2

2,150

0,0000396

GLCE

glucuronic acid epimerase

15q23

2,144

0,0000561

DC2

DC2 protein

4q25

2,143

0,0000181

SMS

spermine synthase

Xp22.1

2,113

0,0003207

GPD2

glycerol-3-phosphate dehydrogenase 2 (mitochondrial)

2q24.1

2,095

0,0000586

LOC283454

hypothetical protein LOC283454

12q24.23

2,095

0,0000465

CXorf57

chromosome X open reading frame 57

Xq22.3

2,094

0,0003208

PTGES3

prostaglandin E synthase 3 (cytosolic)

12.

2,091

0,0000430

HS2ST1

heparan sulfate 2-O-sulfotransferase 1

1p31.1-p22.1

2,080

0,0001750

EMP1

epithelial membrane protein 1

12p12.3

2,066

0,0000357

EBAG9

estrogen receptor binding site associated, antigen, 9

8q23

2,058

0,0000919

VPS37B

vacuolar protein sorting 37 homolog B (S. cerevisiae)

12q24.31

2,049

0,0000640

NOV

nephroblastoma overexpressed gene

8q24.1

2,001

0,0000746

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BMC Cancer

ISSN: 1471-2407

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