Skip to main content

Table 4 Spearman correlations between 7 apoptosis biomarkers and 5 risk factors and 4 clinico-pathologic features1

From: Biomarkers of apoptosis and survival in esophageal squamous cell carcinoma

  FasL Fas FADD pFADD Caspase8 Caspase10 Bcl2
Risk factors        
   Male (yes) 0.17** 0.01 0.05 0.02 -0.02 0.03 0.00
   Age (yrs) -0.01 0.02 -0.06 -0.05 0.10 0.00 0.00
   Tobacco use (yes) 0.17** 0.05 0.08 -0.07 0.00 0.10 0.02
   Alcohol use (daily or weekly) 0.00 -0.02 0.20** -0.09 0.13* 0.09 0.02
   Family history UGI cancer (yes) -0.18** -0.15* 0.00 0.04 -0.05 0.02 -0.01
Clinico-pathologic features        
   Tumor grade (I -- IV) -0.10 -0.20** -0.18** 0.08 -0.07 -0.19** 0.02
   Tumor stage (1 -- 4) 0.00 -0.14* -0.05 0.10 0.01 0.03 0.03
   Lymph node metastasis (yes) 0.02 0.01 -0.04 0.06 0.00 0.01 0.02
Degree differentiation (poor) -0.15* -0.26*** -0.21** 0.03 -0.17** -0.36*** -0.30***
  1. 1 N varies from 235 to 253 and is less than 265 total because none of 7 biomarkers had data for all 265 ESCC cases
  2. * p < 0.05
  3. ** p < 0.01
  4. *** p < 0.0001