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Table 6 GLI1 nuclear immunoreactivity in relation to cytoplasmic SHH reactivity; 187 human tumourous breast tissues

From: Expression of the glioma-associated oncogene homolog (GLI) 1in human breast cancer is associated with unfavourable overall survival

Variable

Categorization

GLI1 nuclear immunoreactivitya

0–6 vs 7–12

  

n analyzable

low

high

Pc

Immunohistochemistry (IHC): 187 human tumourous breast tissues

SHHb

     
 

low (IRS 0–6)

88

45

43

0.000

 

high (IRS 7–12)

99

20

79

 

Immunohistochemistry (IHC): 35 human normal breast tissues

SHHb

     
 

low (IRS 0–6)

23

19

4

0.000

 

high (IRS 7–12)

12

3

9

 
  1. aGLI1 nuclear immunoreactivity: low = IRS 0–6, high = IRS 7–12
  2. bSHH cytoplasmatic immunoreactivity: low = IRS 0–5, high = IRS 6–12
  3. cLog rank test (two-sided), bold face representing significant data (P < 0.05)