Table 1 Results of all intraportal injections with different cell counts of the colon carcinoma cell lines HT-29 and SW-620.
Number of cells | Cell line | Total number of mice | Procedure related mortality (%) | Total number of mice after injection | Number of mice with liver metastases (%) | Number of mice with cytokeratin positivity in bone marrow (%) |
|---|---|---|---|---|---|---|
1 × 105 | HT – 29 | 10 | 0% | 10 | 60% (6/10) | 50% (3/6) |
SW – 620 | 10 | 10% | 9 | 56% (5/9) | 40% (2/5) | |
1 × 106 | HT – 29 | 10 | 10% | 9 | 89% (8/9) | 63% (5/8) |
SW – 620 | 10 | 0% | 10 | 70% (7/10) | 57% (4/7) | |
5 × 106 | HT – 29 | 10 | 30% | 7 | 100% (7/7) | 86% (6/7) |
SW – 620 | 10 | 40% | 6 | 100% (6/6) | 67% (4/6) |