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Table 4 Univariate and multivariate analysis of prognostic indicators on overall survival for colorectal cancer patients

From: Preoperative serum carcinoembryonic antigen, albumin and age are supplementary to UICC staging systems in predicting survival for colorectal cancer patients undergoing surgical treatment

Parameters Number Univariate analysis Multivariate analysis
   Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value
Age (≥65/<65) years 743/624 1.30(1.09–1.56) 0.004 1.85(1.41–2.43) <0.001
Sex (Male/Female) 757/610 1.22(1.03–1.46) 0.026 - 0.186
Site (Colon/Rectum) 920/447 1.20(0.99–1.45) 0.066 - -
Tumor size (≥5/<5) cm 593//774 1.24(1.03–1.50) 0.026 - 0.256
BMIa (≥24/<18.5–24/<18.5) 434/516/417 0.84(0.66–1.09) 0.186 - -
Albumin (<3.5/≥3.5) gm/dl 392/975 1.70(1.38–2.10) <0.001 - 0.072
Histology (PD/MD/WDb) 118/1066/183 2.92(1.91–4.49) <0.001 - 0.245
UICCc stage (III&IV/I&II) 630/737 3.45(2.84–4.18) <0.001 3.09(2.34–4.07) <0.001
CEAd(≥5/<5) ng/ml 643/724 2.74(2.23–3.37) <0.001 2.28(1.73–3.01) <0.001
  1. aBody mass index
  2. bPoorly differentiated; Moderately differentiated; Well differentiated
  3. cInternational Union Against Cancer
  4. dCarcinoembrynic antigen