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Table 2 Association between GNRH1 haplotypes and breast cancer risk in the BPC3 study.

From: Genetic polymorphisms of the GNRH1 and GNRHR genes and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)

Haplotype

Cases (%)

Controls (%)

OR (95% CI)a

p value

hGCT

2,024 (35)

2,697 (35)

1.00 (ref.)

 

hGGT

1,469 (26)

1,955 (26)

1.00 (0.94–1.06)

0.9480

hACC

1,137 (20)

1,487 (19)

1.04 (0.97–1.11)

0.2957

hACT

1,074 (19)

1,484 (19)

0.96 (0.90–1.03)

0.2240

Freq<3%

25 (<1)

34 (<1)

0.87 (0.58–1.31)

0.5056

  1. aOdds ratios and 95% confidence intervals, calculated by unadjusted logistic regression analysis conditional on the matching variables
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BMC Cancer

ISSN: 1471-2407

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