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Table 2 Association between GNRH1 haplotypes and breast cancer risk in the BPC3 study.

From: Genetic polymorphisms of the GNRH1 and GNRHR genes and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)

Haplotype Cases (%) Controls (%) OR (95% CI)a p value
hGCT 2,024 (35) 2,697 (35) 1.00 (ref.)  
hGGT 1,469 (26) 1,955 (26) 1.00 (0.94–1.06) 0.9480
hACC 1,137 (20) 1,487 (19) 1.04 (0.97–1.11) 0.2957
hACT 1,074 (19) 1,484 (19) 0.96 (0.90–1.03) 0.2240
Freq<3% 25 (<1) 34 (<1) 0.87 (0.58–1.31) 0.5056
  1. aOdds ratios and 95% confidence intervals, calculated by unadjusted logistic regression analysis conditional on the matching variables