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Table 3 Association between MGB-2 protein expression and clinicopathological parameters.

From: Mammaglobin B is an independent prognostic marker in epithelial ovarian cancer and its expression is associated with reduced risk of disease recurrence

  

MGB-2 protein expression

 

n

score = 0

score ≥ 1

P*

  

n (%)

n (%)

 

Total

106

64 (60.4)

42 (39.6)

 

Age at diagnosis (y)

    

   ≤ 40

12

6 (50.0)

6 (50.0)

 

   > 40

94

58 (61.7)

36 (38.3)

 
    

0.535

Histological type

    

   endometrioid

19

4 (21.1)

15 (78.9)

 

   clear-cell

11

4 (36.4)

7 (63.6)

 

   undifferentiated

5

4 (80.0)

1 (20.0)

 

   serous-pap.met.

22

19 (86.4)

3 (13.6)

 

   mixed

14

6 (42.9)

8 (57.1)

 

   mucinous

3

2 (66.7)

1 (33.3)

 

   serous-papillary

32

25 (78.1)

7 (21.9)

 
    

<0.001

FIGO stage

    

   ≤ IIB

25

7 (28.0)

18 (72.0)

 

   > IIB

81

57 (70.4)

24 (29.6)

 
    

<0.001

Histological grade

    

   G1

7

2 (28.6)

5 (71.4)

 

   G2

13

6 (46.2)

7 (53.8)

 

   G3

86

56 (65.1)

30 (34.9)

 
    

0.092

Residual tumor (TR), cm

    

   TR = 0

42

18 (42.9)

24 (57.1)

 

   TR ≥ 0.5

64

46 (71.9)

18 (28.1)

 
    

0.004

Ascites

    

   no

44

20 (45.5)

24 (54.5)

 

   yes

62

44 (71.0)

18 (29.0)

 
    

0.010

Lymph nodal involvement

    

   negative

53

27 (50.9)

26 (49.1)

 

   positive

28

21 (75.0)

7 (25.0)

 

   missing

25

16 (64.0)

9 (36.0)

 
    

0.056

Preoperatory CA125 level

    

   < Threshold**

11

4 (36.4)

7 (63.6)

 

   ≥ Threshold**

92

58 (63.0)

34 (37.0)

 

   missing

3

2 (66.7)

1 (33.3)

 
    

0.205

  1. *Fisher exact test.
  2. **Threshold = 200 U/ml for pre-menopausal patients & 35 U/ml for post-menopausal patients.