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Figure 7 | BMC Cancer

Figure 7

From: Cyclophilin C-associated protein (CyCAP) knock-out mice spontaneously develop colonic mucosal hyperplasia and exaggerated tumorigenesis after treatment with carcinogen azoxymethane1

Figure 7

B-catenin cellular localization in WT and CyCAP KO mice. In WT mice, β-catenin expression is higher in the colonic plate than in the crypts of the colon mucosa (A). However, CyCAP KO mice show overall increased membranous expression of β-catenin with irregular distribution, which focally significantly extended into crypts (B). No definite nuclear localization of β-catenin was detected either in WT or KO mice.

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BMC Cancer

ISSN: 1471-2407

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