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Figure 5 | BMC Cancer

Figure 5

From: Cyclophilin C-associated protein (CyCAP) knock-out mice spontaneously develop colonic mucosal hyperplasia and exaggerated tumorigenesis after treatment with carcinogen azoxymethane1

Figure 5

In many early adenomas after azoxymethane treatment, hyperplastic-like changes were also present. Adenomatous changes without (A) and with (B) evidence of cytologic dysplasia and cystically dilated crypts and hyperplastic changes in close proximity to muscularis mucosae were found in tumors after azoxymethane treatment (20 × magnification, H&E).

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