Figure 2From: Carbonic anhydrase 9 is a predictive marker of survival benefit from lower dose of bevacizumab in patients with previously treated metastatic colorectal cancer Survival outcomes according to the CA9 expression scores. The median PFS was 3.9 months and median OS with bevacizumab was 11.4 months; after the 17.6 months of median follow up of all 31 patients. There were statistically significant differences between the 2 groups according to the score in terms of median PFS (4.7 mo vs. 2.4 mo, p = 0.028) and median OS (24.1 mo vs. 10.2 mo, p = 0.026).Back to article page