Table 4 MDR analysis for TNF SNPs and risk of gastric cancer associated with selected combination in MDR stratified by smoking status in a nested case-control study within the KMCC 19,688 enrolled cohort members.

Total

α-857

1.0 (reference)

1.7 (1.0–2.8)*

α-857, α-308

1.0 (reference)

1.8 (1.1–3.0)*

α-863, α-857, α-308

1.0 (reference)

2.2 (1.3–3.7)**

α-1031, α-863, α-857, α-308 ^d

1.0 (reference)

2.2 (1.3–3.6)**

Non-smokers

α-857

1.0 (reference)

1.7 (1.0–2.7)*

α-857, α-308

1.0 (reference)

1.8 (1.1–3.0)*

β 252, α-857, α-308

1.0 (reference)

1.5 (0.9–2.4)

β 252, α-1031, α-857, α-308

1.0 (reference)

1.2 (0.7–2.0)

Smokers

α-857

1.0 (reference)

1.6 (1.0–2.7)*

α-1031, α-857

1.0 (reference)

1.4 (0.9–2.4)

α-1031, α-863, α-857 ^d

1.0 (reference)

2.0 (1.2–3.3)**

α-1031, α-863, α-857, α-308

1.0 (reference)

2.1 (1.3-3.5)**