QRT-PCR of PMC42-LA cells treated for 72 h with 10 ng/ml EGF, 40 nM ST or both. Control: untreated (A) E-cadherin mRNA expression plotted against increased expression of hallmark mesenchymal genes MMP-2 and vimentin. (B) Comparison of expression of four E-cadherin repressor genes in the treatment regime used in A. Error bar values are standard error. Significance was set at p </= 0.05. * symbol indicates a statistically significant difference from the control within each time point. In the combined treatment, ^ and # indicate statistical significance from ST and EGF individual treatments, respectively, within each time point.