The mRNA expression of MMP-2, MMP-7, MMP-9 and MT1-MMP in primary gastric cancer specimens by Real-time PCR. (A) Gastric cancer specimen (T) expressed higher levels of MMP-2, MMP-7, MMP-9 and MT1-MMP compared to matched normal tissue specimens (N). Data are expressed as mean ± SD, n = 32, *P < 0.01, **P < 0.001, vs Normal. (B) SFRP5 expression-negative gastric cancer specimens (SFRP5-) expressed higher levels of MMP-7 and MT1-MMP compared to SFRP5 expression-positive (SFRP5+) gastric cancer specimens. Data are expressed as mean ± SD, n = 24 and 8, respectively, **P < 0.001, vs SFRP5(+).