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Table 3 Odds ratios of breast cancer risk according to level of fish intake

From: Fatty fish and fish omega-3 fatty acid intakes decrease the breast cancer risk: a case-control study

 

Total

Premenopausal women

Postmenopausal women

 

Control (n)

Case (n)

Age adjusted Odds ratio

Multivariate Odds ratioa

Control (n)

Case (n)

Age adjusted Odds ratio

Multivariate Odds ratiob

Control (n)

Case (n)

Age adjusted Odds ratio

Multivariate Odds ratioc

Total fish (g/day)

            

   < 9.99

90

122

1.00 (referent)

1.00 (referent)

47

70

1.00 (referent)

1.00 (referent)

43

52

1.00 (referent)

1.00 (referent)

   9.99-<17.51

90

80

0.65(0.43–0.98)

0.64(0.38–1.07)

49

52

0.69(0.40–1.19)

0.57(0.27–1.19)

41

28

0.57(0.30–1.08)

0.55(0.26–1.19)

   17.51-<33.70

90

80

0.65(0.43–0.98)

0.57(0.34–0.95)

56

44

0.52(0.30–0.90)

0.38(0.18–0.78)

34

36

0.89(0.48–1.67)

1.02(0.47–2.22)

   ≥ 33.70

90

76

0.62(0.41–0.93)

0.55(0.32–0.96)

44

44

0.65(0.37–1.14)

0.49(0.22–1.10)

46

32

0.59(0.32–1.09)

0.62(0.28–1.39)

P for trend

  

0.054

0.063

  

0.157

0.094

  

0.205

0.475

Lean fish (g/day)

            

   < 4.63

90

98

1.00 (referent)

1.00 (referent)

52

56

1.00 (referent)

1.00 (referent)

38

42

1.00 (referent)

1.00 (referent)

   4.63-<8.53

90

70

0.71(0.46–1.08)

0.74(0.43–1.26)

49

45

0.84(0.48–1.46)

0.86(0.42–1.78)

41

25

0.53(0.27–1.04)

0.43(0.19–0.98)

   8.53-<15.27

89

70

0.72(0.47–1.10)

0.61(0.36–1.04)

52

45

0.78(0.45–1.36)

0.60(0.29–1.22)

37

25

0.62(0.31–1.22)

0.50(0.22–1.16)

   ≥ 15.27

91

120

1.20(0.81–1.79)

1.21(0.72–2.04)

43

64

1.34(0.78–2.32)

1.22(0.58–2.57)

48

56

1.07(0.59–1.92)

1.02(0.47–2.21)

P for trend

  

0.102

0.236

  

0.181

0.551

  

0.286

0.328

Fatty fish (g/day)

            

   < 3.42

90

147

1.00 (referent)

1.00 (referent)

44

63

1.00 (referent)

1.00 (referent)

44

69

1.00 (referent)

1.00 (referent)

   3.42-<8.18

90

79

0.53(0.36–0.80)

0.65(0.39–1.08)

50

69

0.64(0.37–1.16)

0.65(0.31–1.35)

44

30

0.43(0.24–0.79)

0.64(0.31–1.31)

   8.18-<15.39

90

91

0.61(0.41–0.91)

0.54(0.32–0.90)

52

55

0.62(0.37–1.04)

0.50(0.25–0.99)

34

32

0.61(0.33–1.14)

0.64(0.29–1.42)

   ≥ 15.39

90

41

0.27(0.17–0.44)

0.23(0.13–0.42)

50

23

0.29(0.16–0.54)

0.19(0.08–0.45)

42

17

0.26(0.13–0.52)

0.27(0.11–0.66)

P for trend

  

< .001

< .001

  

< 0.001

< 0.001

  

< 0.001

0.005

  1. a adjusted for age, BMI, family history of breast cancer, supplement use, education level, occupation, alcohol consumption, smoking status, physical activity, parity, total energy intake, menopausal status, age at menarche; b adjusted for age, BMI, family history of breast cancer, supplement use, education level, occupation, alcohol consumption, smoking status, physical activity, parity, total energy intake, age at menarche; c adjusted for age, BMI, family history of breast cancer, supplement use, education level, occupation, alcohol consumption, smoking status, physical activity, parity, total energy intake, postmenopausal hormone use, age at menarche. Energy-adjusted nutrient intakes were computed as the residuals from the regression model with total caloric intake as the independent variable and absolute nutrient intake as the dependent variable.