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Table 1 ER status is predictive of metastasis in the NKI2 and TRANSBIG data sets.

From: Intrinsic bias in breast cancer gene expression data sets

   

Recurrence Event1

Recurrence2

(ER+ vs ER-)

Data set

ER+ (n)

ER- (n)

ER+ (%)

ER- (%)

HR

p-value

NKI2

225

70

24

47

0.4

<0.0001

Wang

209

77

32

35

0.8

0.5

TRANSBIG

136

64

13

28

0.4

0.005

KJX64/KJ125

149

34

22

29

0.7

0.4

  1. 1. The percentages indicate the proportion of patients that had metastases within 5 years, stratified by the ER status of their primary tumors.
  2. 2. Hazard ratios (HR) and p-values are based on Cox proportional hazards regression analyses and represent the changes in the risk of experiencing a metastatic event for ER positive tumors, as compared to ER negative tumors.