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Table 2 Molecular alterations of EGFR, PDGFRA and VEGFR2 in ASC patients.

From: Molecular characterization of EGFR, PDGFRA and VEGFR2 in cervical adenosquamous carcinoma

Case EGFR PDGFRA VEGFR2
  Mutations IHC* Mutations IHC IHC
1 Q787Q - P567P; V824V; IVS18-50insA +++ ++
2 Normal +++ Normal +++ -
3 Q787Q +++ V824V; IVS18-50insA +++ +++
4 Q787Q +++ V824V; IVS18-50insA +++ +++
5 Q787Q +++ V824V; IVS18-50insA +++ +++
6 Normal + Normal +++ +++
7 Q787Q +++ P567P; IVS14+3G>A +++ ++
8 Q787Q - Normal +++ +++
9 Normal - Normal +++ +++
10 Normal +++ P567P +++ +++
11 Normal - P567P np +++
12 Q787Q - Normal +++ +++
13 Q787Q - Normal ++ +++
14 Normal ++ Normal +++ ++
15 Q787Q + Normal +++ +++
16 Normal +++ P567P +++ +
17 Q787Q - P567P ++ +++
18 Normal - Normal +++ +
19 Q787Q +++ Normal +++ ++
20 Q787Q - Normal +++ +++
21 Normal + P567P np +++
22 Normal ++ P567P +++ +
23 Normal +++ Normal ++ ++
24 Q787Q - Normal ++ +
25 Q787Q + IVS14+49G>A +++ +
26 Q787Q - P567P +++ +++
27 Normal - Normal np ++
28 Q787Q ++ Normal ++ +
29 Q787Q - Normal +++ +
30 Normal +++ Normal ++ +++
  1. IHC: Immunohistochemistry; *: previously reported in [20]; np: not possible due to tissue limitation.