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Figure 1 | BMC Cancer

Figure 1

From: A simple method for co-segregation analysis to evaluate the pathogenicity of unclassified variants; BRCA1 and BRCA2 as an example

Figure 1

Illustration of our model. Hypothetical pedigree for the illustration of our model. Individuals are numbered 1–10 for identification and underneath the age at last contact is listed. Open circle: female, open square: male, closed circle: affected with breast (or ovarian) cancer at age × (BrCx). Unless specified by + (carrier of UV), - (no carrier), individuals are not genotyped. Proband is indicated by arrow.

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