IC50 | HL60 | HL60/DNR | K562 | K56/HHT40 | K562/HHT90 | K562/DOX |
---|---|---|---|---|---|---|
AVE9633 (nM) | 19.9 ± 0.7 | > 800 |  |  |  |  |
AVE9633 + Zosuquidar | 20.1 ± 1.1 | 10.4 ± 2.1 |  |  |  |  |
DM4 (nM) | 14.8 ± 0.3 | > 800 | 11.8 ± 1.1 | 18.4 ± 1.2 | 36.6 ± 2.0 | 437.6 ± 15.1 |
DM4 + Zosuquidar | 18.3 ± 1.3 | 10.9 ± 0.1 | 12.6 ± 1.2 | 6.5 ± 0.6 | 10.1 ± 0.8 | 11.6 ± 0.9 |