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Table 1 Analysis of epithelial cell proliferation in mammary glands and neu-induced hyperplastic mammary lesions by Ki67 immunohistochemistry

From: Freund's vaccine adjuvant promotes Her2/Neu breast cancer

 

Percentage of Proliferating Cells ± SD

Treatment

Terminal End Buds

Ductal/Alveolar Structures

Hyperplastic Mammary Lesions

Saline

56% ± 1

13% ± 1

None

Adjuvant

61% ± 1*

17% ± 1*

None

Saline + neu

N.A.

N.A.

41% ± 2

Adjuvant + neu

N.A.

N.A.

55% ± 2**

  1. N.A.= not analyzed
  2. *P < 0.05, **P < 0.001 (Mann-Whitney Rank test)