Figure 1
From: Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention
Metabolic activation of (A) B[ a ]P and (B) 7,12-DMBA to the carcinogenic metabolites B[ a ]P-7,8-diol, B[ a ]P-7,8-diol-9,10-epoxide and 7,12-DMBA-3,4-diol, 7,12-DMBA-3,4-diol-1,2-epoxide, respectively, by CYP1A1 and epoxide hydrolase [6].