GM3 and pSTAT3 expression. (A) Overview of multiple NSCLC sections stained with 14F7 and examples of cytoplasmic, nuclear and negative staining of 14F7 in NSCLC. (B) Positive or negative nuclear pSTAT3 expression in NSCLC. Open arrows indicate example of nuclear staining; magnifications are indicated. (C) Kaplan-Meier survival analyses for overall survival based on GM3 expression or nuclear pSTAT3 expression in early-stage NSCLC patients. Median expression values were used to generate dichotomous variables. NSCLC, non-small cell lung cancer.