Table 2 Effect of staurosporine on the mobility and invasiveness of A549 cells (
± s, n = 4)
± s, n = 4)Group | Mobility | Invasiveness | ||||
|---|---|---|---|---|---|---|
Cells that penetrate membrane | Mobility inhibition rate | P-value | Cells that penetrate membrane | Invasion inhibition rate | P-value | |
Control group | 149.00 ± 7.12 | 74.50 ± 4.20 | ||||
1 nmol/L staurosporine | 126.50 ± 5.57 | 15% | 0.002 | 62.75 ± 3.86 | 16% | 0.015 |
10 nmol/L staurosporine | 111.75 ± 7.80 | 25% | <0.001 | 46.75 ± 5.91 | 37% | <0.001 |
100 nmol/L staurosporine | 65.50 ± 5.32 | 56% | <0.001 | 34.00 ± 2.94 | 54% | <0.001 |