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Table 4 Uni-factorial analysis and distribution of clinico-pathological factors

From: Survival analysis of 1148 women diagnosed with breast cancer in Southern Iran

Unifactorial analysis Distribution of factors
  Hazard ratio (95%CI) p numbers %
Tumour side    1064 93
   Right 1 0.562 565 49
   Left 1.08 (0.84–1.39)   499 4
Tumour location    440 38
   Lateral 1 0.258 322 28
   Medial 0.75 (0.42–1.36)   68 6
   Central 0.60 (0.30–1.97)   50 4
Tumour size    1055 92
   ≤ 2 cm 1 0.000 298 26
   >2 & <5 cm 1.82 (1.30–2.70)   523 46
   ≥ 5 cm 3.04 (2.05–4.50)   234 20
Tumour grade    1059 92
   Well-differentiated 1 0.000 250 22
   Moderately-differentiated 1.89 (1.28–2.78)   637 55
   Poorly-differentiated 4.53 (2.99–6.86)   172 15
Nuclear grade    140 12
   Low 1 0.068 33 3
   Intermediate 10.88 (1.00–80.75)   91 8
   High 5.70 (0.59–54.90)   16 1
Co-morbidity    352 31
   GI&Respiratory 1 0.433 37 3
   Cardiovascular 0.92 (0.44–1.95)   122 11
   Psycho.&Neurological 0.69 (0.28–1.57)   55 5
   Gynaecologic 1.42 (0.61–3.29)   39 3
   Endocrine&Metabolic 1.13 (0.55–2.33)   99 9
No. of stillbirths    1097 96
   0 1 0.581 997 87
   1–3 1.19 (0.78–1.83)   92 8
   >3 1.48 (0.47–4.62)   8 1
No. of abortions    1106 96
   0 1 0.525 819 71
   1–3 0.85 (0.64–1.14)   269 23
   >3 0.80 (0.30–2.15)   18 2
Histological type    1062 93
   IDC 1 0.086 942 82
   ILC 0.68 (0.31–1.55)   33 3
   Med.C 0.35 (0.14–0.84)   60 5
   MLDC 1.55 (0-.)   3 <1
   Muc.C 0.65 (0.09–4.62)   6 <1
   IPC 1.33 (0.42–4.15)   10 1
   Met.C 3.31 (1.05–10.39)   8 1
No. of excised lymph nodes    1048 91
   0 1 0.007 20 2
   1–10 1.48 (0.46–4.74)   263 23
   11–20 1.93 (0.61–6.09)   553 48
   21–30 2.29 (0.713–7.37)   189 16
   >30 4.67 (1.28–17.03)   23 2
Lymph node ratio    1027 89
   0 1 0.000 331 29
   >0 & ≤ .3 1.98 (1.06–3.66)   246 21
   >.3 & ≤ .6 5.24 (2.96–9.29)   156 14
   >.6 & < 1 11.26 (6.68–18.96)   185 16
   1 18.87 (11.09–32.08)   109 9
No. of involved lymph nodes    1046 91
   0 1 0.000 349 30
   1–5 3.03 (1.82–5.04)   346 30
   6–10 6.59 (3.89–11.15)   146 13
   11–15 10.16 (6.13–16.84)   123 11
   >15 18.78 (11.21–31.45)   82 7
Tumour calcification    1022 89
   No 1 0.000 740 64
   Yes 1.67 (1.28–2.19)   282 25
Tumour necrosis    317 28
   No 1 0.017 157 14
   Yes 1.82 (1.11–2.97)   160 14
Nipple involvement    995 87
   No 1 0.000 887 77
   Yes 1.84 (1.32–2.57)   108 10
Skin involvement    1013 88
   No 1 0.000 946 82
   Yes 2.06 (1.39–3.05)   67 6
Vascular invasion    1035 90
   No 1 0.000 604 53
   Yes 1.90 (1.47–2.46)   431 37
Lymphatic invasion    1006 88
   No 1 0.000 419 36
   Yes 3.73 (2.67–5.20)   587 52
Treatment    1134 99
   S&C&R 1 0.000 927 81
   C&S&R 1.86 (1.39–2.50)   178 16
   S&R 1.27 (0.56–2.87)   29 2
Type of surgery    1065 93
   MRM 1 0.000 649 57
   RM 1.09 (0.64–1.86)   62 5
   TM 1.60 (1.13–2.28)   99 9
   L 0.58 (0.37–0.90)   164 14
   Q 0.32 (0.14–0.73)   85 7
   PM 2.66 (0.85–8.36)   6 1
  1. Abbreviations: IDC = Invasive Ductal Carcinoma, ILC = Invasive Lobular Carcinoma, Med.C = Medullary Carcinoma, MLDC = Mixed Lobular Ductal Carcinoma, Muc.C = Mucinous Carcinoma, IPC = Invasive Papillary Carcinoma, Met.C = Metaplastic Carcinoma, S&C&R = Surgery and Chemotherapy and Radiotherapy, C&S&R = Chemotherapy and Surgery and Radiotherapy, S&R = Surgery and Radiotherapy, MRM = Modified Radical Mastectomy, RM = radical Mastectomy, TM = Total Mastectomy, L = Lumpectomy, Q = Quadrantectomy, PM = Partial Mastectomy