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Table 2 Weighted Kappa statistics on the whole cohort for comparison of inter-observer concordance for categorized HER2 IHC variables (n = 1212)

From: Inter-observer reproducibility of HER2 immunohistochemical assessment and concordance with fluorescent in situhybridization (FISH): pathologist assessment compared to quantitative image analysis

 

Visual 1

Visual 2

Machine 1

Visual 1

-

-

-

Visual 2

0.929 (0.909 – 0.946)

-

-

Machine 1

0.835 (0.806 – 0.862)

0.837 (0.810 – 0.862)

-

Machine 2

0.698 (0.672 – 0.723)

0.709 (0.684 – 0.732)

0.806 (0.785 – 0.826)