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Table 7 Logistic regression for association between moderate to very severe nausea and vomiting and diarrhoea and B symptoms and other potential predictor variables.

From: Inflammatory (B) symptoms are independent predictors of myelosuppression from chemotherapy in Non-Hodgkin Lymphoma (NHL) patients – analysis of data from a British National Lymphoma Investigation phase III trial comparing CHOP to PMitCEBO

 

Univariate OR#

(95% CI@)

p

Multivariate OR#

(95% CI@)

p

Nausea and vomiting*

    

B symptoms present

1.5 (1.0–2.3)

0.049

-

 

Performance status level 2–4

2.4 (1.6–3.8)

< 0.001

2.6 (1.6–4.0)

< 0.001

Male sex

0.5 (0.3–0.8)

0.001

0.5 (0.3–0.7)

0.001

PMitCEBO given

0.5 (0.3–0.8)

0.004

0.5 (0.3–0.8)

0.003

Diarrhoea**

    

B symptoms present

1.9 (1.2–3.0)

0.004

-

 

Performance status level 2–4

3.1 (2.0–4.9)

< 0.001

3.2 (2.0–5.0)

< 0.001

Age 75 years or older

1.8 (1.2–2.9)

0.009

1.9 (1.2–3.1)

0.006

Stage 3 or 4

1.5 (0.9–2.4)

0.088

-

 
  1. * The multivariate model is for 599 patients with complete data on all variables included in it.
  2. ** The multivariate model is for 600 patients with complete data on all variables included in it.
  3. # Odds ratio
  4. @ Confidence interval