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Table 7 Logistic regression for association between moderate to very severe nausea and vomiting and diarrhoea and B symptoms and other potential predictor variables.

From: Inflammatory (B) symptoms are independent predictors of myelosuppression from chemotherapy in Non-Hodgkin Lymphoma (NHL) patients – analysis of data from a British National Lymphoma Investigation phase III trial comparing CHOP to PMitCEBO

  Univariate OR#
(95% CI@)
p Multivariate OR#
(95% CI@)
p
Nausea and vomiting*     
B symptoms present 1.5 (1.0–2.3) 0.049 -  
Performance status level 2–4 2.4 (1.6–3.8) < 0.001 2.6 (1.6–4.0) < 0.001
Male sex 0.5 (0.3–0.8) 0.001 0.5 (0.3–0.7) 0.001
PMitCEBO given 0.5 (0.3–0.8) 0.004 0.5 (0.3–0.8) 0.003
Diarrhoea**     
B symptoms present 1.9 (1.2–3.0) 0.004 -  
Performance status level 2–4 3.1 (2.0–4.9) < 0.001 3.2 (2.0–5.0) < 0.001
Age 75 years or older 1.8 (1.2–2.9) 0.009 1.9 (1.2–3.1) 0.006
Stage 3 or 4 1.5 (0.9–2.4) 0.088 -  
  1. * The multivariate model is for 599 patients with complete data on all variables included in it.
  2. ** The multivariate model is for 600 patients with complete data on all variables included in it.
  3. # Odds ratio
  4. @ Confidence interval