Figure 5From: Tumor-directed gene therapy in mice using a composite nonviral gene delivery system consisting of the piggyBac transposon and polyethylenimine In vivo sensitivity of the HSV-tk transfected cells to GCV (Magnification, ×200). (A) The PB/TK transfected cells are shown as bright red. (B) Apoptotic cells are bright green after staining with TUNEL assay kit. (C) The merged cells (yellow) suggest the transfected cells were undergoing apoptosis after GCV treatment in vivo.Back to article page