Figure 3

FAK and adhesion modulate v-Src-induced phosphorylation of p120catenin. Lysates from adherent or suspension cultures of FAK+/+[puro], FAK-/-[puro], FAK+/+[v-Src] and FAK-/-[v-Src] cells were probed by IB for total p120catenin, p120cateninpoY228 or GAPDH. These data are typical of at least three independent experiments. Arrows, p120catenin identified by the p120cateninpoY228-specific Ab.