From: Prognostic scores in brain metastases from breast cancer
Parameter | Univariate analysis (log rank test) | Multivariate analysis (Cox regression analysis) | Included in final prognostic model |
---|---|---|---|
Primary tumor control | not done | Â | Â |
Age | not significant (p = 0.09) | not significant (p > 0.01) | Â |
Karnofsky performance status | p < 0.05 | p = 0.01, hazard ratio 3.6 | yes |
Extracranial metastases | p < 0.05 | p = 0.03, hazard ratio 2.1 | yes |
Interval from first cancer diagnosis to brain metastases | p < 0.05 | p = 0.05, hazard ratio 1.8 | yes |
Number of brain metastases | p < 0.05 | p = 0.05, hazard ratio 2.0 | yes |
Diameter of the largest brain metastasis | not significant (p > 0.1) | not included | Â |
Hormone receptor status | not significant (p > 0.1) | not included | Â |