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Table 3 Overview of prognostic factors in the present group of patients

From: Prognostic scores in brain metastases from breast cancer

Parameter Univariate analysis (log rank test) Multivariate analysis (Cox regression analysis) Included in final prognostic model
Primary tumor control not done   
Age not significant (p = 0.09) not significant (p > 0.01)  
Karnofsky performance status p < 0.05 p = 0.01, hazard ratio 3.6 yes
Extracranial metastases p < 0.05 p = 0.03, hazard ratio 2.1 yes
Interval from first cancer diagnosis to brain metastases p < 0.05 p = 0.05, hazard ratio 1.8 yes
Number of brain metastases p < 0.05 p = 0.05, hazard ratio 2.0 yes
Diameter of the largest brain metastasis not significant (p > 0.1) not included  
Hormone receptor status not significant (p > 0.1) not included  
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