Figure 3From: The subcellular localization of IGFBP5 affects its cell growth and migration functions in breast cancer Wild-type IGFBP5 mainly localized at the cellular nucleolus. IGFBP5 wt/pDsRed2-N1 and B23/pGFP constructs were co-transfected into MBA-MD-435 cells. After 48 h post-transfection, the cells were fixed and counterstained with DAPI. The IGFBP5 fusion protein showed co-localization with B23, which is a marker for the nucleolus.Back to article page