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Table 1 Frequency of Ex4+199 G>C (72Pro) allele

From: Haplotype analysis of TP53 polymorphisms, Arg72Pro and Ins16, in BRCA1 and BRCA2 mutation carriers of French Canadian descent

   Genotypic frequencies (%) P values Allele frequencies (%) HWE
Group Sampl number e GG (Arg, Arg) GC (Arg, Pro) CC (Pro, Pro) All cases BRCA2+ BRCA- G C P value
Controls 112 57 (50.9) 46 (41.1) 9 (8.0) 0.84    160 (71.4) 64 (28.6) 1
All cases 157 80 (51.0) 67 (42.7) 10 (6.3)     227 (72.3) 87 (27.7) 0.55
BRCA1+ 42 20 (47.6) 18 (42.9) 4 (9.5)   0.86 0.47 58 (69.0) 26 (31.0) 1
BRCA2+ 57 29 (50.9) 24 (42.1) 4 (7.0)    0.78 82 (71.9) 32 (28.1) 1
BRCA- 58 31 (53.4) 25 (43.1) 2 (3.4)     87 (75.0) 29 (25.0) 0.47
BRCA1/2+ 99 49 (49.5) 42 (42.5) 8 (8.0)    0.57 140 (70.7) 58 (29.3) 1