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Table 2 Association of the PHB_1630_C > T polymorphism with ovarian cancer risk in BRCA1 carriers

From: Ovarian cancer risk in Polish BRCA1 mutation carriers is not associated with the prohibitin 3' untranslated region polymorphism

  All cases and controls
Genotype Cases (n = 127) n (%) Controls (n = 127) n (%) ORcrude b (95% CI) p
PHB_1630_C > T     
   CC 101 (80) 102 (80) 1.00 (reference)  
   CT+TTa 26 (20) 25 (20) 1.05 (0.54–2.04) 1.00
  Cases and controls with risk factor information
Genotype Cases (n = 83) n (%) Controls (n = 83) n (%) ORadj c (95% CI) p
PHB_1630_C > T     
   CC 64 (77) 65 (78) 1.00(reference)  
   CT+TTa 19 (23) 18 (18) 1.34 (0.59–3.11) 0.49
  1. a Due to the low proportion of <3% in patients and controls, CT and TT genotypes were combined.
  2. b ORcrude: crude odds ratio.
  3. c ORadj: odds ratio adjusted for age at menarche, age of first live birth, parity, breastfeeding, OC use, HRT, smoking and BMI.