Table 3 Numbers of cases aged 15–24 years, age-standardized rates (per million population) and 95% CIs, average annual percentage rate changes and 95% CIs, by diagnosis, sex and time period and test for sex-difference in temporal trend (P-value)
1968–1980 | 1981–1993 | 1994–2005 | % Ann Inc | M/F diff | |||||
|---|---|---|---|---|---|---|---|---|---|
CNS tumours | Male | 87 | 29.0 (22.9,35.1) | 84 | 28.4 (22.3,34.5) | 53 | 23.6 (17.3,30.0) | -0.5 (-1.9,0.8) | 0.60 |
Female | 59 | 19.8 (14.7,24.8) | 59 | 20.2 (15.1,25.4) | 47 | 20.8 (14.9,26.8) | 0.0 (-1.5,1.5) | ||
Ependymomas | Male | 8 | 2.7 (1.2,5.3) | 10 | 3.4 (1.6,6.3) | 3 | 1.3 (0.3,3.9) | -2.1 (-5.5,1.4) | 0.19 |
Female | 2 | 0.7 (0.1,2.5) | 1 | 0.4 (0.0,2.1) | 3 | 1.3 (0.3,3.9) | 3.2 (-3.9,10.3) | ||
Astrocytomas | Male | 28 | 9.4 (6.2,13.6) | 25 | 8.6 (5.6,12.7) | 23 | 10.2 (6.5,15.3) | 0.4 (-1.9,2.7) | 0.71 |
Female | 21 | 7.0 (4.4,10.8) | 17 | 5.8 (3.4,9.3) | 16 | 7.1 (4.0,11.5) | -0.2 (-2.4,2.0) | ||
PNET | Male | 8 | 2.6 (1.1,5.2) | 3 | 1.0 (0.2,2.9) | 2 | 0.9 (0.1,3.2) | -2.8 (-7.9,2.2) | 0.99 |
Female | 4 | 1.4 (0.4,3.5) | 2 | 0.7 (0.1,2.5) | 1 | 0.5 (0.0,2.6) | -2.9 (-8.8,3.1) | ||
Other gliomas | Male | 14 | 4.6 (2.5,7.8) | 17 | 5.6 (3.3,9.0) | 5 | 2.2 (0.7,5.2) | -1.4 (-4.4,1.5) | 0.99 |
Female | 11 | 3.6 (1.8,6.5) | 10 | 3.6 (1.7,6.7) | 5 | 2.2 (0.7,5.1) | -1.4 (-5.3,2.4) | ||
Sympathetic nervous system tumours | Male | 1 | 0.3 (0.0,1.8) | 6 | 2.1 (0.8,4.6) | 2 | 0.9 (0.1,3.2) | 1.5 (-4.1,7.0) | 0.71 |
Female | 2 | 0.7 (0.1,2.4) | 3 | 1.1 (0.2,3.1) | 4 | 1.9 (0.5,4.8) | 3.1 (-3.4,9.7) | ||
Retinoblastoma | Male | 0 | - | 0 | - | 0 | - | - | - |
Female | 0 | - | 0 | - | 0 | - | - | ||
Renal tumours | Male | 1 | 0.3 (0.0,1.8) | 3 | 1.0 (0.2,2.9) | 4 | 1.7 (0.5,4.3) | 2.8 (-4.0,9.6) | 0.32 |
Female | 3 | 1.0 (0.2,3.0) | 3 | 0.9 (0.2,2.7) | 1 | 0.4 (0.0,2.4) | -1.8 (-7.9,4.3) | ||
Hepatoblastomas | Male | 0 | - | 0 | - | 0 | - | - | - |
Female | 1 | 0.3 (0.0,1.8) | 1 | 0.3 (0.0,1.7) | 0 | - | -4.4 (-16.0,7.3) | ||
Bone tumours | Male | 36 | 12.1 (8.2,16.1) | 50 | 17.7 (12.8,22.6) | 28 | 12.6 (8.4,18.3) | 0.2 (-1.7,2.0) | 0.15 |
Female | 19 | 6.4 (3.9,10.0) | 22 | 7.9 (4.9,11.9) | 25 | 11.6 (7.5,17.1) | 2.2 (0.2,4.2) | ||
Osteosarcoma | Male | 20 | 6.8 (4.2,10.6) | 23 | 8.2 (5.2,12.3) | 17 | 7.7 (4.5,12.3) | 0.1 (-2.6,2.8) | 0.10 |
Female | 10 | 3.4 (1.6,6.2) | 12 | 4.3 (2.2,7.5) | 17 | 7.9 (4.6,12.7) | 3.5 (0.5,6.5) | ||
Ewing's sarcoma | Male | 9 | 3.0 (1.4,5.7) | 20 | 7.0 (4.3,10.8) | 7 | 3.2 (1.3,6.6) | 1.0 (-1.9,4.0) | 0.50 |
Female | 6 | 2.1 (0.8,4.5) | 5 | 1.7 (0.6,4.1) | 5 | 2.3 (0.8,5.4) | -0.7 (-4.8,3.4) | ||
Soft tissue sarcomas | Male | 27 | 9.1 (6.0,13.3) | 29 | 9.9 (6.6,14.2) | 33 | 14.6 (9.6,19.6) | 1.9 (-0.4,4.2) | 0.55 |
Female | 27 | 9.2 (6.1,13.4) | 39 | 13.3 (9.1,17.5) | 28 | 12.7 (8.4,18.4) | 1.0 (-0.8,2.9) | ||
Rhabdomyosarcoma | Male | 5 | 1.7 (0.6,4.0) | 2 | 0.7 (0.1,2.6) | 7 | 3.2 (1.3,6.6) | 3.0 (-1.5,7.5) | 0.74 |
Female | 4 | 1.4 (0.4,3.6) | 13 | 4.6 (2.5,7.9) | 4 | 1.8 (0.5,4.5) | 2.0 (-2.2,6.1) | ||
Other | Male | 22 | 7.4 (4.6,11.2) | 27 | 9.1 (6.0,13.3) | 26 | 11.4 (7.5,16.7) | 1.7 (-1.0,4.4) | 0.60 |
Female | 23 | 7.8 (4.9,11.7) | 26 | 8.7 (5.7,12.7) | 24 | 10.9 (7.0,16.3) | 0.7 (-1.7,3.2) | ||
Germ cell tumours | Male | 70 | 23.1 (17.7,28.6) | 115 | 37.5 (30.6,44.4) | 107 | 46.5 (37.7,55.3) | 2.1 (0.6,3.7) | 0.74 |
Female | 44 | 14.6 (10.3,18.9) | 35 | 11.6 (7.8,15.5) | 48 | 21.6 (15.5,27.7) | 1.7 (-0.2,3.6) | ||
Gonadal | Male | 65 | 21.5 (16.2,26.7) | 101 | 32.8 (26.4,39.3) | 94 | 40.9 (32.6,49.1) | 1.9 (0.3,3.4) | 0.51 |
Female | 29 | 9.6 (6.4,13.8) | 26 | 8.6 (5.6,12.7) | 31 | 13.8 (9.0,18.7) | 1.0 (-1.0,3.0) | ||
Non-gonadal | Male | 5 | 1.7 (0.5,3.9) | 14 | 4.6 (2.5,7.8) | 13 | 5.6 (3.0,9.6) | 4.4 (1.1,7.7) | 0.65 |
Female | 15 | 5.0 (2.8,8.2) | 9 | 3.0 (1.4,5.7) | 17 | 7.8 (4.5,12.4) | 3.2 (-0.7,7.1) | ||
Carcinomas | Male | 78 | 25.7 (20.0,31.4) | 75 | 24.6 (19.0,30.2) | 68 | 29.7 (22.6,36.8) | 0.2 (-1.4,1.8) | 0.07 |
Female | 131 | 43.1 (35.7,50.5) | 164 | 53.9 (45.6,62.1) | 177 | 78.2 (66.7,89.7) | 2.2 (0.7,3.7) | ||
Thyroid | Male | 6 | 2.0 (0.7,4.3) | 8 | 2.8 (1.2,5.5) | 9 | 3.9 (1.8,7.4) | 2.5 (-2.2,7.2) | 0.90 |
Female | 13 | 4.4 (2.3,7.5) | 22 | 7.4 (4.6,11.3) | 26 | 11.5 (7.5,16.9) | 2.8 (0.1,5.6) | ||
Melanoma | Male | 20 | 6.7 (4.1,10.4) | 22 | 7.2 (4.5,10.9) | 19 | 8.3 (5.0,13.0) | 0.6 (-2.1,3.3) | 0.03 |
Female | 25 | 8.3 (5.3,12.2) | 54 | 17.8 (13.0,22.5) | 69 | 30.8 (23.5,38.1) | 4.6 (2.2,7.1) | ||
Skin | Male | 9 | 2.9 (1.3,5.5) | 9 | 2.9 (1.3,5.5) | 21 | 9.1 (5.6,13.8) | 4.7 (0.5,8.9) | 0.61 |
Female | 11 | 3.6 (1.8,6.5) | 12 | 4.1 (2.1,7.1) | 20 | 8.8 (5.4,13.6) | 3.2 (-0.4,6.9) | ||
Breast | Male | 0 | - | 0 | - | 1 | 0.5 (0.0,2.6) | 11.8 (-8.4,32.0) | 0.25 |
Female | 14 | 4.5 (2.5,7.6) | 18 | 5.7 (3.4,9.0) | 10 | 4.3 (2.1,8.0) | -0.3 (-2.9,2.3) | ||
Genital/other reproductive | Male | 0 | - | 0 | - | 0 | - | - | - |
Female | 31 | 10.0 (6.5,13.5) | 28 | 8.8 (5.9,12.8) | 26 | 11.3 (7.4,16.6) | 0.5 (-1.7,2.8) | ||
Lung and bronchial | Male | 4 | 1.3 (0.4,3.4) | 3 | 1.0 (0.2,2.9) | 0 | - | -6.2 (-12.5,0.2) | 0.23 |
Female | 2 | 0.7 (0.1,2.4) | 1 | 0.3 (0.0,1.7) | 2 | 0.9 (0.1,3.3) | 0.0 (-7.7,7.8) | ||
Colorectal | Male | 10 | 3.3 (1.6,6.1) | 5 | 1.7 (0.6,4.0) | 4 | 1.7 (0.5,4.4) | -3.5 (-7.4,0.4) | 0.01 |
Female | 1 | 0.3 (0.0,1.8) | 3 | 1.0 (0.2,2.9) | 5 | 2.2 (0.7,5.0) | 8.2 (0.1,16.3) | ||
TOTAL | Male | 300 | 99.8 (88.5,111.1) | 362 | 121.1 (108.6,133.6) | 295 | 129.7 (114.9,144.5) | 0.8 (-0.2,1.8) | 0.30 |
Female | 286 | 95.2 (84.1,106.2) | 326 | 109.2 (97.3,121.1) | 330 | 147.2 (131.3,163.1) | 1.6 (0.5,2.7) |