Table 10 Meta-analysis – Survival in 15 trials comparing gemcitabine to gemcitabine + cytotoxic agent
Groups | n trials | n patients | HR | p | 95% CI |
|---|---|---|---|---|---|
Gemcitabine versus Gemcitabine + Platinum Analog | 5 | 1248 | 0.85 | 0.010 | 0.76 – 0.96 |
Gemcitabine versus Gemcitabine + Fluoropyrimidine | 6 | 1813 | 0.90 | 0.03 | 0.81 – 0.99 |
Gemcitabine versus Gemcitabine + other cytotoxic agent | 4 | 1404 | 0.99 | 0.80 | 0.88 – 1.10 |
Total | 15 | 4465 | 0.91 | 0.004 | 0.85 – 0.97 |