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Table 10 Meta-analysis – Survival in 15 trials comparing gemcitabine to gemcitabine + cytotoxic agent

From: Meta-analysis of randomized trials: evaluation of benefit from gemcitabine-based combination chemotherapy applied in advanced pancreatic cancer

Groups n trials n patients HR p 95% CI
Gemcitabine versus Gemcitabine + Platinum Analog 5 1248 0.85 0.010 0.76 – 0.96
Gemcitabine versus Gemcitabine + Fluoropyrimidine 6 1813 0.90 0.03 0.81 – 0.99
Gemcitabine versus Gemcitabine + other cytotoxic agent 4 1404 0.99 0.80 0.88 – 1.10
Total 15 4465 0.91 0.004 0.85 – 0.97