Table 3 Immunohistochemical features of 123 cases of invasive mammary carcinomas according to axillary lymph node status
IHC features | Mac-Met n (%) | Mic-Met n (%) | LNN n (%) | Total n (%) |
|---|---|---|---|---|
ER * | Â | Â | Â | Â |
Positive | 31 (75.6) | 35 (85.4) | 34 (82.9) | 100 (81.3) |
Negative | 10 (24.4) | 6 (14.6) | 7 (17.1) | 23 (18.7) |
PR * | Â | Â | Â | Â |
Positive | 25 (61) | 29 (70.7) | 28 (68.3) | 82 (66.7) |
Negative | 16 (39) | 12 (29.3) | 13 (31.7) | 41 (33.3) |
Her2/ neu score | Â | Â | Â | Â |
0 and 1+ | 35 (85.4) | 32 (78) | 36 (87.8) | 103 (83.7) |
2+ | 1 (2.4) | 1 (2.4) | 1 (2.4) | 3 (2.4) |
3+ | 5 (12.2) | 8 (19.5) | 4 (9.8) | 17 (13.8) |
P53 | Â | Â | Â | Â |
Positive | 17 (41.5) | 11 (26.8) | 10 (24.4) | 38 (30.9) |
Negative | 24 (58.5) | 30 (73.2) | 31 (75.6) | 85 (69.1) |
Ki67 score * | Â | Â | Â | Â |
<10% | 16 (39) | 23 (56.1) | 16 (39) | 55 (44.7) |
10–25% | 11 (26.8) | 9 (22) | 13 (31.7) | 33 (26.8) |
25–50% | 10 (24.4) | 6 (14.6) | 8 (19.5) | 24 (19.5) |
>50% | 4 (9.8) | 3 (7.3) | 4 (9.8) | 11 (8.9) |
E-cadherin score | Â | Â | Â | Â |
0 (negative) | 2 (4.9) | 1 (2.4) | 2 (4.9) | 5 (4.1) |
1+ | 3 (7.3) | 3 (7.3) | 2 (4.9) | 8 (6.5) |
2+ | 0 (0) | 2 (4.9) | 1 (2.4) | 3 (2.4) |
3+ | 8 (19.5) | 6 (14.6) | 4 (9.8) | 18 (14.6) |
4+ | 28 (68.3) | 29 (70.7) | 32 (78) | 89 (72.4) |
Total | 41 (100) | 41 (100) | 41 (100) | 123 (100) |