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Table 2 Clinicopathologic features of 123 cases of invasive mammary carcinomas according to axillary lymph node status

From: Lymph vascular invasion in invasive mammary carcinomas identified by the endothelial lymphatic marker D2-40 is associated with other indicators of poor prognosis

Characteristics

Mac-Met n (%)

Mic-Met n (%)

LNN n (%)

Total n (%)

Age

    

≤ 52 years

22 (53.7)

21 (51.2)

20 (48.8)

63 (51.2)

>52 years

19 (46.3)

20 (49.8)

21 (51.2)

60 (49.8)

Menopausal status

    

Premenopausal

20 (48.8)

18 (43.9)

20 (48.8)

58 (47.2)

Postmenopausal

21 (51.2)

23 (56.1)

21 (51.2)

65 (52.8)

Tumor Size (TNM)

    

T1

10 (24.4)

17 (41.5)

17 (41.5)

44 (35.8)

T2

24 (58.5)

23 (56.1)

18 (43.9)

65 (52.8)

T3

7 (17.1)

1 (2.4)

6 (14.6)

14 (11.4)

Histologic type

    

Ductal NST

36 (87.8)

33 (80.4)

36 (87.8)

105 (85.4)

Lobular

3 (7.4)

5 (12.2)

2 (4.8)

10 (8.1)

Other type

2 (4.8)

3 (7.4)

3 (7.4)

8 (6.5)

Histologic grade*

    

Grade I

9 (22)

14 (34.1)

13 (31.7)

36 (29.3)

Grade II

21 (51.2)

18 (43.9)

19 (46.3)

58 (47.2)

Grade III

11 (26.8)

9 (22)

9 (22)

29 (23.6)

Total

41 (100)

41 (100)

41 (100)

123 (100)

  1. Mac-Met = macrometastases; Mic-Met = micrometastases; LNN = lymph node negative; n = number of cases; NST = non-special type
  2. *Tumors with lymphatic invasion showed a higher histologic grade (p = 0.013). This correlation with lymphatic invasion was significant in H&E-sections and also in IHC-sections.