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Table 2 Clinicopathologic features of 123 cases of invasive mammary carcinomas according to axillary lymph node status

From: Lymph vascular invasion in invasive mammary carcinomas identified by the endothelial lymphatic marker D2-40 is associated with other indicators of poor prognosis

Characteristics Mac-Met n (%) Mic-Met n (%) LNN n (%) Total n (%)
Age     
≤ 52 years 22 (53.7) 21 (51.2) 20 (48.8) 63 (51.2)
>52 years 19 (46.3) 20 (49.8) 21 (51.2) 60 (49.8)
Menopausal status     
Premenopausal 20 (48.8) 18 (43.9) 20 (48.8) 58 (47.2)
Postmenopausal 21 (51.2) 23 (56.1) 21 (51.2) 65 (52.8)
Tumor Size (TNM)     
T1 10 (24.4) 17 (41.5) 17 (41.5) 44 (35.8)
T2 24 (58.5) 23 (56.1) 18 (43.9) 65 (52.8)
T3 7 (17.1) 1 (2.4) 6 (14.6) 14 (11.4)
Histologic type     
Ductal NST 36 (87.8) 33 (80.4) 36 (87.8) 105 (85.4)
Lobular 3 (7.4) 5 (12.2) 2 (4.8) 10 (8.1)
Other type 2 (4.8) 3 (7.4) 3 (7.4) 8 (6.5)
Histologic grade*     
Grade I 9 (22) 14 (34.1) 13 (31.7) 36 (29.3)
Grade II 21 (51.2) 18 (43.9) 19 (46.3) 58 (47.2)
Grade III 11 (26.8) 9 (22) 9 (22) 29 (23.6)
Total 41 (100) 41 (100) 41 (100) 123 (100)
  1. Mac-Met = macrometastases; Mic-Met = micrometastases; LNN = lymph node negative; n = number of cases; NST = non-special type
  2. *Tumors with lymphatic invasion showed a higher histologic grade (p = 0.013). This correlation with lymphatic invasion was significant in H&E-sections and also in IHC-sections.