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Table 1 Sex, age smoking (in pack years) and histological subtypes of lung cancer in the study samples

From: Do genetic factors protect for early onset lung cancer? A case control study before the age of 50 years

 

Cases

Controls

Sample size

246

223

Sex (m/f)

185/61 (~3:1)

167/56 (~3:1)

 

Male

Female

Male

Female

Age (mean +/- sd)

45.5 ± 4.1

44.9 ± 4.9

44.8 ± 3.9

44.9 ± 3.3

   24–40 years

21 (11%)

7 (11%)

19 (11%)

6 (11%)

   41–45 years

57 (31%)

18 (30%)

61 (37%)

24 (43%)

   46–50 years

107 (58%)

36 (59%)

87 (52%)

26 (46%)

Smoking

    

   Packyears (mean +/- sd)*

32.3 ± 17.5

26.2 ± 12.4

27.1 ± 13.3

14.6 ± 10.2

   never and light smoker (≤1 PY)

7 (4%)

8 (14%)

66 (65%)

32 (73%)

   moderate smoker (1-<20 PY)

40 (23%)

14 (24%)

12 (12%)

9 (20%)

   heavy smoker (20-PY)

130 (73%)

37 (63%)

23 (23%)

3 (7%)

   former smoker

4

--

66

12

Histological subtype

    

Small-cell (SCLC)

45 (24%)

20 (33%)

  

Adenocarcinoma

54 (29%)

23 (37%)

  

Squamous-cell carcinoma (SCC)

55 (30%)

9 (15%)

  

Others

31 (17%)

9 (15%)

  

Total

185

61

  
  1. * for controls packyears (py) have been calculated from the current amount of cigarette consumption per day and the duration of smoking
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BMC Cancer

ISSN: 1471-2407

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